Norak Transfluor® Publications 

1. Robert Oakley, Christine Hudson, Rachael Cruickshank, Diane Meyers, Richard

Payne, Jr., Shay Rhem, and Carson Loomis. (2002). The Cellular Distribution of

Fluorescently Labeled Arrestins Provides a Robust, Sensitive, and Universal

Assay for Screening G Protein-Coupled Receptors. ASSAY and Drug

Development Technologies 1(1): 21-30.

2. Christine Hudson, Robert Oakley, Rachael Cruickshank, Shay Rhem, and

Carson Loomis. (2002). Automation and Validation of the Transfluor®

Technology: a Universal Screening Assay for G Protein-coupled Receptors.

Proceedings of SPIE. Volume 4626: 548-55.

GPCR Desensitization Mechanism Publications from Scientific Founders

1. Ahn S, Nelson CD, et al. (2003) Desensitization, internalization, and signaling

functions of beta-arrestins demonstrated by RNA interference. Proc Natl Acad

Sci U S A 100(4):1740-4

2. Attramadal, H., J. L. Arriza, et al. (1992). Beta-arrestin2, a novel member of the

arrestin/beta-arrestin gene family. J Biol Chem 267(25): 17882-17890.

3. Barak, L. S., S. S. Ferguson, et al. (1997). A beta-arrestin/green fluorescent

protein biosensor for detecting G protein-coupled receptor activation. J

Biol Chem 272(44): 27497-500.

4. Barak, L. S., S. S. Ferguson, et al. (1997). Internal trafficking and surface

mobility of a functionally intact beta2-adrenergic receptor-green

fluorescent protein conjugate. Mol Pharmacol 51(2): 177-84.

5. Barak, L. S., L. Menard, et al. (1995). The conserved seven-transmembrane

sequence NP(2,3Y of the G-protein-coupled receptor superfamily regulates

multiple properties of the beta 2-adrenergic receptor. Biochemistry 34(47):


6. Barak, L. S., R. H. Oakley, et al. (2001). Constitutive arrestin-mediated

desensitization of a human vasopressin receptor mutant associated with

nephrogenic diabetes insipidus. Proc Natl Acad Sci U S A 98: 93-98.